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portada Invertebrate Cytokines and the Phylogeny of Immunity(Springer pg)
Type
Physical Book
Publisher
Author
Language
English
Pages
184
Format
Paperback
ISBN13
9783642622366

Invertebrate Cytokines and the Phylogeny of Immunity(Springer pg)

Beschin Alain,Müller Werner E. G. (Author) · Springer Pg · Paperback

Invertebrate Cytokines and the Phylogeny of Immunity(Springer pg) - Beschin Alain,Müller Werner E. G.

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Synopsis "Invertebrate Cytokines and the Phylogeny of Immunity(Springer pg)"

Based on the assumption that invertebrates as well as vertebrates possess factors regulating hematopoiesis, response to infection or wounding, studies dealing with the evolution of immunity have focused on the isolation and characterization of putative cytokine-related molecules from invertebrates. Until recently, most of our knowledge of cytokine- and cytokine receptor-like molecules in invertebrates has relied on functional assays and similarities at the physicochemical level. As such, a phylogenetic relationship between invertebrate cytokine-like molecules and invertebrate counterparts could not be convincingly demonstrated. In the present book, recent studies demonstrating cytokine-like activities and related signaling pathways in invertebrates are critically reviewed, focusing on findings from molecular biology and taking advantage of the completion of the genome from the fly Drosophila and the worm Caenorhabditis elegans.

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