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portada Mitochondria and Brain Disorders
Type
Physical Book
Publisher
Author
Language
English
Pages
126
Format
Hardcover
Dimensions
24.4x17x1 cm
Weight
0.40 kg.
ISBN13
9781789855319
Categories

Mitochondria and Brain Disorders

Baloyannis, Stavros (Author) · Intechopen · Hardcover

Mitochondria and Brain Disorders - Baloyannis, Stavros

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Synopsis "Mitochondria and Brain Disorders"

The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to common neurological diseases, such as Parkinson's disease, Alzheimer's disease, Friedreich's ataxia, Huntington's disease, and Multiple Sclerosis. An efficient treatment of mitochondrial dysfunction would open new horizons in the therapeutic perspectives of a substantial number of inflammatory and degenerative neurological disorders.

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The binding of this edition is Hardcover.

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