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portada myeloid leukemia
Type
Physical Book
Illustrated by
Publisher
Author
Language
English
Pages
320
Format
Paperback
Dimensions
23.1x19.6x1.5 cm
Weight
0.45 kg.
ISBN
1607614561
ISBN13
9781607614562
Categories

myeloid leukemia

Harry Iland (Illustrated by) · Mark Hertzberg (Illustrated by) · Paula Marlton (Illustrated by) · Humana · Paperback

myeloid leukemia - Iland, Harry ; Hertzberg, Mark ; Marlton, Paula

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Synopsis "myeloid leukemia"

A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.

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