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portada Surface Modification of Polymer Constructs for Tissue Engineering
Type
Physical Book
Year
2012
Language
English
Pages
180
Format
Paperback
ISBN
3844386726
ISBN13
9783844386721

Surface Modification of Polymer Constructs for Tissue Engineering

Laleh Safinia (Author) · Lap Lambert Academic Publishing · Paperback

Surface Modification of Polymer Constructs for Tissue Engineering - Laleh Safinia

New Book Imported to Taiwan
Delivery: 13 Oct - 21 Oct Shipping: 13 to 14 business days.
NT$ 2,509
NT$ 2,509

Synopsis "Surface Modification of Polymer Constructs for Tissue Engineering "

One of the major issues in tissue engineering is the seeding of mammalian cells onto natural or synthetic scaffolds, to which the cells should attach and colonise into three-dimensional (3D) orientation, defining the shape of the tissue. The structural and surface properties of the biomaterials used to make the scaffolds, such as pore structure, hydrophilicity and surface charge are therefore important parameters to consider, if they are to be used as supportive 3D matrices for cells, providing a strong mechanical contact between the cells and the scaffold. In this work, a variety of synthetic polymer scaffolds was fabricated via thermally induced phase separation (TIPS) followed by freeze-drying. The polymers under study were two biodegradable polyesters, poly (D,L-lactide) (PDLLA) and poly (lactide-co-glycolide) (PLGA) and two non-biodegradable polymers, polystyrene (PS) and polyurethane (PU). For the design and reproducible fabrication of polymer scaffolds, tailored for directed tissue growth, pore structure and surface chemistry of the selected polymer scaffolds were studied.

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