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portada Bone Morphogenetic Proteins: Methods and Protocols (Methods in Molecular Biology)
Type
Physical Book
Publisher
Year
2018
Language
English
Pages
265
Format
Hardcover
ISBN13
9781493989034
Edition No.
1
Categories

Bone Morphogenetic Proteins: Methods and Protocols (Methods in Molecular Biology)

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Synopsis "Bone Morphogenetic Proteins: Methods and Protocols (Methods in Molecular Biology) "

This volume provides methods to study bone morphogenetic proteins (BMPs) and BMP modulators in cell culture, in both invertebrate and vertebrate animal models, and for therapeutic applications. Chapters guide the reader in the use of primary and immortalized cell lines, methodologies that exploit transcription and receptor mechanisms, newly developed animal models using nematodes, flies, amphioxus, frogs, zebrafish, and genetically engineered mice, and pre-clinical approaches to understanding BMP function in bone regeneration, heterotopic ossification, and cancers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and cutting-edge, Bone Morphogenetic Proteins: Methods and Protocols aims to ensure successful results in the further study of this vital field.

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