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portada Molecular Chaperones and Cell Signalling
Type
Physical Book
Illustrated by
Publisher
Author
Year
2011
Language
English
Pages
346
Format
Paperback
Dimensions
22.9 x 15.2 x 2.0 cm
Weight
0.51 kg.
ISBN
0521177472
ISBN13
9780521177474
Edition No.
1
Categories

Molecular Chaperones and Cell Signalling

Brian Henderson (Illustrated by) · A. Graham Pockley (Illustrated by) · Cambridge University Press · Paperback

Molecular Chaperones and Cell Signalling - Henderson, Brian ; Pockley, A. Graham

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Delivery: 07 Sep - 15 Sep Shipping: 5 to 6 business days.
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NT$ 2,061

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Synopsis "Molecular Chaperones and Cell Signalling "

This book reviews understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first and foremost protein-folding molecules. Paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been introduced is discussed. The role of exogenous molecular chaperones as cell regulators is examined and the physiological and pathophysiological role that molecular chaperones play is described. In the final section, the potential therapeutic use of molecular chaperones is described and the final chapter asks the question - what does the future hold for the extracellular biology of molecular chaperones?

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