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portada Entropy-Enthalpy Compensation: Finding a Methodological Common Denominator Through Probability, Statistics, and Physics
Type
Physical Book
Year
2020
Language
English
Pages
418
Format
Hardcover
ISBN13
9789814877305
Edition No.
1

Entropy-Enthalpy Compensation: Finding a Methodological Common Denominator Through Probability, Statistics, and Physics

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Synopsis "Entropy-Enthalpy Compensation: Finding a Methodological Common Denominator Through Probability, Statistics, and Physics "

Professionals recognize entropy-enthalpy compensation as an important factor in molecular recognition, lead design, water networks, and protein engineering. It can be experimentally studied by proper combinations of diverse spectroscopic approaches with isothermal titration calorimetry and is clearly related to molecular dynamics. So, how should we treat entropy-enthalpy compensation? Is it a stubborn hindrance that solely complicates the predictability of phenomena otherwise laid on the line by Mother Nature? How should we then deal with it? This book dwells on these posers. It combines two chapters written by globally recognized specialists. Chapter 1 deals with general issues and suggests a definite approach to how we may answer the posers. Chapter 2 shows how the approach outlined might be successfully applied in a rational design of enzymes. This might provide other interesting strategic perspectives in the general theoretical physical chemistry field.

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The book is written in English.
The binding of this edition is Hardcover.

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