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portada IGE Antibodies: Generation and Function
Type
Physical Book
Publisher
Author
Language
English
Pages
152
Format
Paperback
Dimensions
23.4x15.6x0.9 cm
Weight
0.24 kg.
ISBN13
9783319358888
Categories

IGE Antibodies: Generation and Function

Lafaille, Juan J. ; Curotto De Lafaille, Maria A. (Author) · Springer · Paperback

IGE Antibodies: Generation and Function - Lafaille, Juan J. ; Curotto De Lafaille, Maria A.

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Synopsis "IGE Antibodies: Generation and Function"

This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.

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