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portada Implementation of Genome Transposition in GRIMM
Type
Physical Book
Author
Publisher
Language
English
Pages
60
Format
Paperback
Dimensions
22.9 x 15.2 x 0.4 cm
Weight
0.10 kg.
ISBN13
9786139966738
Categories

Implementation of Genome Transposition in GRIMM

Rafi Imran Noor (Author) · Nabila Binte Alam (Author) · Saroar Ahmed (Author) · LAP Lambert Academic Publishing · Paperback

Implementation of Genome Transposition in GRIMM - Noor, Rafi Imran ; Alam, Nabila Binte ; Ahmed, Saroar

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Synopsis "Implementation of Genome Transposition in GRIMM"

In Computational biology, genome rearrangement by transposition is an important problem. Genome evolution analysis by transpositions leads to a combinatorial optimization problem of sorting by transpositions. Though the status of the transposition distance problem was open, a non-trivial proof for the NP-completeness of the transposition median problem is given [2]. In this work, we utilize a 1.375-approximation algorithm for sorting by transpositions [16]. GRIMM is a tool for analyzing rearrangements in pairs of genomes, including unichromosomal and multichromosomal genomes, and signed and unsigned data. In GRIMM, reversal is the only operation for unichromosomal genome rearrangement. In this book, we implement transposition in GRIMM as another unichromosomal operation.

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