Name: Macrophages: Biology and Role in the Pathology of Diseases
Price: 6435.00 TWD
Availability: InStock
Author: Biswas, Subhra K. ; Mantovani, Alberto
ISBN: 9781493954872

portada Macrophages: Biology and Role in the Pathology of Diseases

Macrophages: Biology and Role in the Pathology of Diseases

Type

Physical Book

Publisher

Springer

Author

Biswas, Subhra K. ; Mantovani, Alberto

Language

English

Pages

615

Format

Paperback

ISBN13

9781493954872

Synopsis "Macrophages: Biology and Role in the Pathology of Diseases"

Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morphogenesis and ductal branching in mammary glands. Thus, macrophages are extremely versatile cells that can respond efficiently to tissue micro environmental cues by polarizing to distinct phenotypes, depending on the functions they need to perform. Indeed, functional diversity and plasticity are hallmarks of these cells.Macrophages may also play a detrimental role. An overwhelming body of literature has indicated their crucial role in pathogenesis. The list includes sepsis, cancer, metabolic syndrome, immunodeficiency, auto-immune disease-virtually impacting every major pathology that we know. These observations have suggested macrophages and their related molecules as potential targets in therapeutic applications. Available evidence proclaims macrophages as a key player in homeostasis, host defense and disease. Crucial developments in the past few years call for a re-evaluation and update of our understanding of macrophages. The present book is an endeavour that attempts provide state-of-the art knowledge of these cells in health and disease.

Customers reviews

Have you read this book? Login to add your review.

More customer reviews

0% (0)
0% (0)
0% (0)
0% (0)
0% (0)

Questions and Answers about the Book

Do you have a question about the book? Login to be able to add your own question.

Opinions about Bookdelivery

More customer reviews

Macrophages: Biology and Role in the Pathology of Diseases - Biswas, Subhra K. ; Mantovani, Alberto

Synopsis "Macrophages: Biology and Role in the Pathology of Diseases"

Customers reviews

Frequently Asked Questions about the Book

Is the book original?

In what language is the book written?

What is the format of this book?

Questions and Answers about the Book

Opinions about Bookdelivery