Mathematical Representation of Kidney Function - Alan M. Weinstein

This monograph provides a comprehensive review of mathematical modeling of kidney transport. It sits at the intersection of mathematical biology and renal physiology. The content is organized according to multiscale model development: from membrane transporters, to polarized cell construction, cell function within epithelia, elaboration of kidney tubule segments, configuration of the whole nephron, and finally formulation of a kidney consisting of nephrons and blood vessels. The concluding chapter reviews several outstanding unsolved problems in mathematical modeling of kidney function and offers a possible approach for future workers.