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portada Microfluidics and Multi Organs on Chip
Type
Physical Book
Publisher
Author
Language
English
Pages
717
Format
Paperback
ISBN13
9789811913815
Categories

Microfluidics and Multi Organs on Chip

Mohanan, P. V. (Author) · Springer · Paperback

Microfluidics and Multi Organs on Chip - Mohanan, P. V.

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Synopsis "Microfluidics and Multi Organs on Chip"

This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.

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