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portada Proteinkinase Inhibitors
Type
Physical Book
Publisher
Author
Language
English
Pages
256
Format
Paperback
Dimensions
23.4x15.6x1.4 cm
Weight
0.38 kg.
ISBN13
9783030681821
Categories

Proteinkinase Inhibitors

Laufer, Stefan (Author) · Springer · Paperback

Proteinkinase Inhibitors - Laufer, Stefan

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Synopsis "Proteinkinase Inhibitors"

This book reviews the principles of design and examples of successful implementation of proteinkinase inhibitors (PKI), and offers a comprehensive and authoritative overview of the history and latest developments in the field. Chapters written by experts from industry and academia cover the function, structure and topology of Proteinkinases, molecular modelling, disclose how to achieve high level of selectivity for kinase inhibitors, and exploit kinase inhibitors for cancer treatment. Particular attention is given to Inhibitors of c-Jun N-terminal kinase 3, and to covalent Janus Kinase 3 Inhibitors. A case study on Receptor Tyrosine Kinases EGFR, VEGFR, PDGFR is also presented in this book.Given its breath, this book will appeal to medicinal chemists, students, researchers and professionals alike.

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