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portada Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders
Type
Physical Book
Illustrated by
Publisher
Author
Language
English
Pages
604
Format
Paperback
ISBN13
9780443186776
Edition No.
1
Categories

Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

Heba Mohamed Mansour (Illustrated by) · Mahmoud Mohamed Khattab (Illustrated by) · Aiman Saad El-Khatib (Illustrated by) · Academic Press · Paperback

Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders - Mansour, Heba Mohamed ; Khattab, Mahmoud Mohamed ; El-Khatib, Aiman Saad

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Synopsis "Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders "

Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders. Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered. Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitors (RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia. In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders.

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