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portada Sickle Cell Anemia: From Basic Science to Clinical Practice
Type
Physical Book
Publisher
Author
Language
English
Pages
435
Format
Hardcover
Dimensions
24.1x15.6x2.8 cm
Weight
1.02 kg.
ISBN13
9783319067124
Categories

Sickle Cell Anemia: From Basic Science to Clinical Practice

Costa, Fernando Ferreira ; Conran, Nicola (Author) · Springer · Hardcover

Sickle Cell Anemia: From Basic Science to Clinical Practice - Costa, Fernando Ferreira ; Conran, Nicola

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Synopsis "Sickle Cell Anemia: From Basic Science to Clinical Practice"

Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated with the disease. Our knowledge regarding sickle cell disease mechanisms, while still not complete, has broadened considerably over the last decades. Sickle Cell Anemia: From Basic Science to Clinical Practice aims to provide an update on our current understanding of the disease's pathophysiology and use this information as a basis to discuss its manifestations in childhood and adulthood. Current therapies and prospects for the development of new approaches for the management of the disease are also covered.

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