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portada Untranslated Gene Regions and Other Non-Coding Elements: Regulation of Eukaryotic Gene Expression
Type
Physical Book
Author
Publisher
Language
English
Pages
56
Format
Paperback
Dimensions
22.6 x 15.2 x 0.5 cm
Weight
0.14 kg.
ISBN13
9783034806787
Categories

Untranslated Gene Regions and Other Non-Coding Elements: Regulation of Eukaryotic Gene Expression

Lucy W. Barrett (Author) · Sue Fletcher (Author) · Steve D. Wilton (Author) · Springer · Paperback

Untranslated Gene Regions and Other Non-Coding Elements: Regulation of Eukaryotic Gene Expression - Barrett, Lucy W. ; Fletcher, Sue ; Wilton, Steve D.

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Synopsis "Untranslated Gene Regions and Other Non-Coding Elements: Regulation of Eukaryotic Gene Expression"

There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as "junk DNA", it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5' and 3' untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.​

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