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portada Nanoantimicrobials
Type
Physical Book
Author
Publisher
Language
English
Pages
52
Format
Paperback
Dimensions
22.9x15.2x0.3 cm
Weight
0.09 kg.
ISBN13
9786206981763
Categories

Nanoantimicrobials

Paulina Laura Páez (Author) · Vanina Paola Veas (Author) · María Gabriela Paraje (Author) · Our Knowledge Publishing · Paperback

Nanoantimicrobials - Veas, Vanina Paola ; Páez, Paulina Laura ; Paraje, María Gabriela

New Book Imported to Taiwan
Delivery: 13 Oct - 21 Oct Shipping: 13 to 14 business days.
NT$ 1,543
NT$ 1,543

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Synopsis "Nanoantimicrobials"

Candida has the ability to adhere to surfaces and form biofilms that can be up to a thousand times more resistant to antimicrobials. Nanoparticles (NPs) obtained by biological synthesis (green synthesis) are of particular interest because they are environmentally friendly. An emerging strategy is to combine NPs such as silver (NPAg) with antifungals (ATF) used in the clinic, in search of synergy. Studies were conducted with biosynthesised NPAg alone and combined with an ATF such as amphotericin B (AmB) against mature Candida biofilms. C. albicans and C. tropicalis strains were used, biofilms were formed and the activity of NPAg, AmB, and the combination of NPAg + AmB was evaluated. It was quantified by crystal violet staining. In addition, the biofilm structure was observed by brightfield and fluorescence optical microscopy. In mature C. albicans biofilm, the biosynthesised Ag NPs, alone and in combination, showed significant antibiofilm activity. These results are encouraging as a possible strategy for the treatment of biofilm-resistant fungal infections.

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