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portada The Functional Matrix Hypothesis - Revisited
Type
Physical Book
Publisher
Author
Language
English
Pages
52
Format
Paperback
Dimensions
22.9x15.2x0.3 cm
ISBN13
9786209312519

The Functional Matrix Hypothesis - Revisited

Parveen, Asma; Kumar H. C., Kiran; Kareem, Tanhaz (Author) · LAP Lambert Academic Publishing · Paperback

The Functional Matrix Hypothesis - Revisited - Parveen, Asma; Kumar H. C., Kiran; Kareem, Tanhaz

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Synopsis "The Functional Matrix Hypothesis - Revisited"

The Functional Matrix Hypothesis (FMH), proposed by Melvin L. Moss in the 1960s, established a paradigm shift in craniofacial biology by attributing skeletal growth primarily to the functional demands of soft tissues rather than intrinsic bone determinants. Moss proposed that bone responds secondarily to changes in functional matrices such as muscles, orofacial spaces, and neurocranial contents. Over the decades, empirical evidence from animal models, human developmental studies, and orthodontic clinical practice has expanded and modified FMH. Contemporary knowledge integrates FMH with epigenetics, mechanotransduction, and systems biology, offering a refined understanding of craniofacial growth. This review synthesizes historical foundations, theoretical principles, biological mechanisms, clinical applications, and modern interpretations of FMH, highlighting its relevance and limitations in orthodontic diagnosis and treatment planning.

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